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home > Medical/Hormonal > Library > A Sticky Solution to Transdermal Adhesion Problems

A Sticky Solution to Transdermal Adhesion Problems

Important Note: This solution only applies to transdermal patches that have an outer adhesive ring with an inner medication surface. 

In theory, the transdermal skin patch provides a method for delivering medication through the wearer's skin barrier, ideally making it a convenient and consistent route for drug delivery.

However, in its real world application, the transdermal patch does not always provide the same ease and consistency as oral administration. Transdermal medication delivery, that is, the passing of medication from its delivery area through the skin's surface, requires solid contact.  But transdermal patches do not always stay tightly bound to the skin's surface.

For those not familiar with the patch, it is comprised of a medication delivery area, somewhat larger than a quarter-dollar coin, which is encircled by an adhesive area.  The transdermal patch, which in transgender usage dispenses either estradiol or testosterone, looks very much like an oversized circular bandage.  And like the typical adhesive bandage, the patch does not always stay put. 

Depending on our conditions, we perspire, we are exposed to a damp or humid climate, and are physically active to a point of loosening the patch.

While bandages need only to cover the affected area and usually can be easily reaffixed or replaced, patches need to be in consistent contact to work properly.  Patches are not easily replaced as they are costly, and prematurely changing out patches may affect dosing.

For those who continue to have difficulties, even while following an accepted Transdermal Application Guideline, a sticky solution in the form of tincture of Benzoin may prove to solve transdermal adhesion problems.  Check with your doctor or pharmacist about using tincture of Benzoin.

Tincture of Benzoin is a brown, pungent liquid that becomes sticky and is used to adhere things to the skin in clinical applications. It is an alcohol based plant product and can be obtained without a prescription. In clinical applications, it is usually available in larger bottles or aerosol containers. For individual use, a pharmacy will likely need to order a one to two once bottle. 

Pre-packaged benzoin coated swabs may also be available at locations that sell products for outdoor enthusiasts, as it is a product that typically complements the hiker's and camper's first-aid kit.

If one chooses to use benzoin, apply the liquid only to the skin that will later be in contact with the adhesive area of the patch, not to the medication delivery area.  At the time of application, take care so the skin is clean and dry, allow the benzoin to air dry for about thirty seconds, then apply the patch. Check the patch to assure that is properly sealed at the edge.  The tincture will increase adhesion and, as it reduces sweating, benzoin will also prolong adhesion.

By using this sticky solution, the transdermal patch should remain solidly in place even in the most demanding of environments.


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